A randomised trial of 5% minoxidil versus combination of 5% minoxidil and oral spironolactone in treatment of female pattern hair loss

A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss.

BACKGROUND To pical minoxidil solution 2% stimulates new hair growth and helps stop the loss of hair in men with androgenetic alopecia and women with female pattern hair loss. Results can be variable, and historic experience suggests that higher concentrations of topical minoxidil may enhance efficacy. OBJECTIVE The purpose of this 48-week, double-blind, placebo-controlled, randomized, multic...

Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone.

BACKGROUND Minoxidil and spironolactone are oral antihypertensives known to stimulate hair growth. OBJECTIVE To report on a case series of women with pattern hair loss (PHL) treated with once daily minoxidil 0.25 mg and spironolactone 25 mg. METHODS Women newly diagnosed with a Sinclair stage 2-5 PHL were scored for hair shedding and hair density before and after 12 months of treatment with...

Efficacy and safety of 5% minoxidil topical foam in male pattern hair loss treatment and patient satisfaction.

INTRODUCTION Male pattern hair loss is widespread around the world. Its prevalence indicates the importance of finding the best treatment modalities. This study evaluates the efficacy and safety of minoxidil 5% topical foam in male pattern hair loss treatment and patient satisfaction. METHODS This study was a before-and-after trial on 17 male patients with male pattern hair loss. Subjects wer...

Evaluation and treatment of male and female pattern hair loss

Minoxidil in combination with Tretinoin vs. Minoxidil in the treatment of male androgenic alopecia: A randomized, double-blind, parallel clinical trial

Background: Minoxidil is currently an approved treatment for androgenetic alopecia. Topical tretinoin can enhance skin absorption of minoxidil. Objective: This study has been done in order to determine the efficacy and safety of the solution of 0.5% minoxidil+0.05% tretinoin compared to 2% minoxidil in androgenetic alopecia in men. Patients and Methods: In a randomized, double-blind, parallel-g...